文獻(xiàn)：使用磁性納米探針進(jìn)行脂質(zhì)體和非脂質(zhì)體藥物藥代動(dòng)力學(xué)研究的快速有效技術(shù)及其在脂質(zhì)體泄漏動(dòng)力學(xué)中的應(yīng)用

鏈接：https://www.sciencedirect.com/science/article/abs/pii/S0021967318313086

作者：陳云娜，王雷 ，郭東東 ，陳明盛，戴浩 志 ，小燕 石 ，張文靜 ，黃倩倩 ，彭 燦，陳衛(wèi)東 

節(jié)選：

DTX脂質(zhì)體的表征

本研究采用乙醇注入法制備了含有DSPE-PEG2000-生物素的DTX-脂質(zhì)體。測(cè)定了DTX-脂質(zhì)體的粒徑、PDI和zeta電位，結(jié)果如圖S1所示。DTX-脂質(zhì)體的平均粒徑、PDI和zeta電位分別為177.2 nm、0.203和-14.7 mV。PDI小于0.3表示脂質(zhì)體粒徑分布均勻。包封率約為98%，載藥量約為3.3%。DTX載藥脂質(zhì)體的形態(tài)

Characterization of the DTX-liposomes

In this study, DTX-liposomes with DSPE-PEG2000-biotin were prepared using ethanol injection method. The particle size, PDI and zeta potential of the DTX-liposomes were determined and shown in Fig. S1. The average particle size, PDI and zeta potential of DTX-liposomes were 177.2?nm, 0.203 and ?14.7?mV, respectively. The PDI less than 0.3 mean the size of liposomes was distributed uniformly. The encapsulation efficiency was about 98% with loading capacity about 3.3%. The morphology of DTX-loaded

西安pg電子官方生物提供相關(guān)產(chǎn)品：

RGD-PEG-OH

DODAP (18:1)

DSPE-PEG-GRGDS

DSPE-PEG-SCM

DSPE-PEG-Lectins

DSPE-Rhodamine B/DSPE-RhB

DSPE-PEG-Dethiobiotin

DSPE-PEG-Cy3

DSPE-PEG-Glucose

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