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ICG NHS ester ;ICG-NHS 吲哚菁綠-活性酯;CAS:622335-40-3 吲哚菁綠琥珀酰亞胺脂

英文名：ICG NHS ester

中文名：吲哚菁綠-琥珀酰亞胺酯

吲哚菁綠-活性酯

CAS No: 1622335-40-3

分子式: C49H53N3O7S

分子量: 828.03

外 觀：綠色粉末

溶解性：溶于DMSO或DMF

純 度：95%

保 存：-20避光

激發(fā)發(fā)射波長(zhǎng):785/821nm

產(chǎn)品描述：

ICG is a NIR fluorescent substance which obtain license for clinical uses from US FDA(Food and Drug administration), along with Methylene Blue. It is used in Ophthalmologic angiography, liver function tests, solid tumor detection in surgical operation and angiography.

Because ICG effectively absorbs near infrared wavelength that is about 800nm and its absorption ratio for wavelength of visible light range is low, noises caused by Autofluorescence is low.

ICG NHS ester is a product that has the most representative NHS ester reactive group for labeling amine. Because it rapidly and high-specifically reacts to Primary amine (-NH2), it can label Protein containing amine (-NH2), Antibody and Amine-modified Oligonucleotide in a short time period.

ICG是一種近紅外熒光物質(zhì)，與亞甲基藍(lán)一起獲得美國(guó)食品和**管理局(FDA)的臨床使用許可。它用于眼科血管造影、肝功能檢測(cè)、外科手術(shù)中的實(shí)體瘤檢測(cè)和血管造影。

由于ICG能**吸收800nm左右的近紅外波長(zhǎng)，且對(duì)可見(jiàn)光波長(zhǎng)的吸收率較低，因此自發(fā)熒光產(chǎn)生的噪聲較低。

ICG NHS酯是一種具有最具代表性的NHS酯反應(yīng)基團(tuán)的產(chǎn)品，用于標(biāo)記胺。由于它對(duì)伯胺(-NH2)反應(yīng)迅速且特異性高，因此可以在短時(shí)間內(nèi)標(biāo)記含胺(-NH2)、抗體和胺修飾寡核苷酸的蛋白質(zhì)。