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          Luteoloside,5373-11-5
          發(fā)布時間:2023-03-20     作者:hao   分享到:

          產(chǎn)品名稱:

          Luteoloside,5373-11-5

          產(chǎn)地:西安

          規(guī)格:1mg 5mg 10mg

          純度:99%

          用途:僅用于科研

          溫馨提示:僅用于科研,不能用于人體實驗!

          Luteoloside is a flavonoid that has been found in many Chinese herbs with diverse biological activities.1,2,3,4 It reduces lactate dehydrogenase (LDH) and caspase-3 activities and production of reactive oxygen species (ROS) and increases cell viability and 14-3-3η protein levels in H9C2 cardiomyocytes after anoxia/reoxygenation injury.1 Luteoloside blocks 3C protease activity (IC50 = 0.36 mM) and reduces the cytopathic effect of enterovirus 71 in rhabdomyosarcoma cells (EC50 = 0.43 mM).2 It inhibits the growth of hepatocellular carcinoma (HCC) cells in vitro via reduction in ROS accumulation, caspase-1 activity, and expression of the NLRP3 inflammasome and reduces the number of lung metastases in an SMMC-7721 HCC mouse xenograft model when administered at a dose of 2 mg/kg.3 Luteoloside also reduces acanthosis and expression of epidermal differentiation markers in a mouse model of psoriasis induced by imiquimod (Item No. 14956).4

          Luteoloside,5373-11-5

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          編輯:XAQYBIO HAO,2023年3月15日。

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