產(chǎn)品名稱:
9(E),11(E),13(E)-Octadecatrienoic Acid,544-73-0
產(chǎn)地:西安
規(guī)格:1mg 5mg 10mg
純度:99%
用途:僅用于科研
溫馨提示:僅用于科研,不能用于人體實驗!
9(E),11(E),13(E)-Octadecatrienoic acid (β-ESA) is a conjugated polyunsaturated fatty acid that is found in plant seed oils and in mixtures of conjugated linolenic acids synthesized by the alkaline isomerization of linolenic acid.1 It reduces growth of Caco-2 colon cancer cells in a dose-dependent and time-dependent manner. In vitro, β-ESA induces DNA fragmentation and upregulation of pro-apoptotic Bax mRNA. β-ESA decreases protein expression of the apoptosis suppression factor Bcl-2 and induces apoptosis in T24 bladder cancer cells via production of reactive oxygen species.2 It also inhibits bacterial fatty acid dioxygenase with a Ki value of 49 nM in vitro.
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編輯:XAQYBIO HAO,2023年3月15日。