產(chǎn)品名稱：

Isoconazole (nitrate)，24168-96-5

產(chǎn)地：西安

規(guī)格：1mg 5mg 10mg

純度：99%

用途：僅用于科研

溫馨提示：僅用于科研，不能用于人體實(shí)驗(yàn)！

Isoconazole is an imidazole with antimicrobial activity.1 It is active against clinical isolates of Candida species, including C. albicans, C. parapsilosis, C. tropicalis, C. krusei, and C. guilliermondii with MIC values ranging from 0.12 to 2 μg/ml. It is also active against the fungi T. mentagrophytes and T. rubrum when used at a concentration of 0.1 ?g/ml and the bacteria C. tuberculostearicum, methicillin-resistant S. aureus (MRSA), and S. epidermis (MICs = 3.9, 32, and 5.6 mg/L, respectively).2,3 Isoconazole induces the production of reactive oxygen species (ROS) in S. aureus.3 It also inhibits heme oxygenase in rat spleen and rat brain microsomes that endogenously express high levels of heme oxygenase-1 (HO-1) and HO-2, respectively (IC50s = 5.6 and 32.6 ?M, respectively).

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編輯：XAQYBIO HAO，2023年3月15日。